Melbourne ResearchAnimal Ethics

GM and cloned animals

When ???genetically modified??? is selected to describe an animal on an ethics application at the University of Melbourne, it will generate a further series of questions. Answers to these questions enable the Animal Ethics Committee (AEC) to assess the extent to which modifications affect the health and welfare of animals and whether their generation is justified.
Title
Guidelines for the generation, breeding, care and use of genetically modified and cloned animals for scientific purposes (pdf, 1.3mb)
Source
National Health and Medical Research Council, 2006
Status
Guidelines
Description
A succinct guide detailing the welfare issues an AEC focuses on when assessing animal research involving GM or cloned animals. The following sections are most relevant to researchers:
  1. Scope of the impact on animals incl. monitoring (p.17)
  2. Reporting requirements of Investigators (p.19)
  3. Reduction, refinement and replacement (p. 20)
  4. Animal husbandry incl. methods to verify DNA transmission (p. 21)
  5. Determination of the phenotype (p. 23)

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